Detection of Early Pregnancy Forms of Human Chorionic Gonadotropin by Home Pregnancy Test Devices
نویسندگان
چکیده
منابع مشابه
Detection of early pregnancy forms of human chorionic gonadotropin by home pregnancy test devices.
BACKGROUND Home pregnancy testing devices claim >99% diagnostic accuracy for pregnancy and utility on the first day of the missed menses or earlier. We investigated the forms of human chorionic gonadotropin (hCG) in early pregnancy urines, the diagnostic accuracy claim, and the abilities of 15 devices to detect the different forms of hCG. METHODS We measured the concentrations of regular hCG ...
متن کاملHuman chorionic gonadotropin testing for early pregnancy viability and complications.
Human chorionic gonadotropin (hCG) is a heterogeneous molecule that is the marker of choice for detecting pregnancy and indicating ectopic pregnancies and spontaneous abortions. This article describes the use of hCG in detecting pregnancy, and how pregnancy detection is complicated by the extreme variation in individual hCG results and by the varying structure of hCG. The problems of false-posi...
متن کاملA test of maternal human chorionic gonadotropin during pregnancy as an adaptive filter of human gestations.
The risk of abnormalities and morbidity among live births increases with advanced maternal age. Explanations for this elevated morbidity invoke several maternal mechanisms. The relaxed filter stringency (RFS) hypothesis asserts that mothers, nearing the end of their reproductive lifespan, reduce the stringency of a screen of offspring quality in utero based on life-history traits of parity and ...
متن کاملHuman chorionic gonadotropin isoforms in the diagnosis of ectopic pregnancy.
BACKGROUND Early diagnosis of ectopic pregnancy uses ultrasound with serial measurements of total human chorionic gonadotropin (hCG). The objective of this study was to explore the possibility that an isolated measurement of hCG isoforms/subunits rather than total hCG could be used as a single test for ectopic pregnancy. METHODS Total and intact hCG, free hCG beta- and alpha-subunits (hCGbeta...
متن کاملApplication of Bayesian Latent Variable Model for Early Detection of Gestational Diabetes Mellitus Without A Perfect Reference Standard Test by β‐human Chorionic Gonadotropin
Background and Objectives: Gestational diabetes mellitus (GDM) is a medical problem in pregnancy, and its late diagnosis can cause adverse effects in the mother and fetus. The purpose of this research was to estimate the accuracy parameters of a biomarker for early prediction of gestational diabetes in the absence of a perfect reference standard test. Methods: This study was conducted in 52...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2001
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/47.12.2131